Primary hyperparathyroidism with normal serum intact parathyroid hormone levels

Persistent elevated serum levels of intact parathyroid hormone after reoperation for primary hyperparathyroidism and after pamidronate therapy.

Primary hyperparathyroidism is a life-threatening rare disorder. It is seen as a result of neonatal primary hyperparathyroidism, familial hypocalciuric hypercalcemia, increased vitamin D levels and inactivation of calcium sensing receptor mutations. The clinical findings are hypotonia, bone demineralization, hypercalcemia and parathyroid hyperplasia. We present a six-month-old female patient, t...

Parathyroid hormone-related peptide and primary hyperparathyroidism.

The parathyroid hormone-related peptide (PTHrP) has been shown to be the major pathogenic factor to humoral hypercalcemia of malignancy (HHM). The presence of PTHrP in many normal tissues and in normal or abnormal parathyroids has been described in literature and its role has been investigated. PTHrP release from parathyroid cells into the extracellular space has been demonstrated to depend on ...

Rapid intraoperative determination of intact parathyroid hormone during surgery for primary hyperparathyroidism. Experience at our center.

INTRODUCTION Primary hyperparathyroidism (PHPT) is due to a single adenoma in 85%-95% of cases, and is often cured after adenoma removal. Intraoperative rapid determination of intact parathyroid hormone (PTHio) may be a tool for monitoring the effectiveness of PHPT surgery. The main objective of our study was to evaluate PTHio determination and to establish whether its successful implementation...

Falsely normal values of intact parathyrin in serum of patients with mild primary hyperparathyroidism?

serum levels of intact parathyroid hormone, calcium, and phosphorus and risk of mortality in hemodialysis patients

conclusions while high serum pth, calcium, and phosphorus levels could determine the mortality risk in hemodialysis patients, decreased serum phosphorus and pth levels were in association with malnutrition and comorbidities and were not independent risk factors for mortality. background abnormal mineral metabolism is common among hemodialysis patients and has been associated with higher morbidi...